Short-term safety and effects of a novel fully bioabsorable poly-L-lactic acid sirolimus-eluting stents in porcine coronary arteries
摘要The role of drug-eluting stent (DES),which prevents acute or subacute recoil and elutes drugs to prevent smooth muscle cell proliferation,is temporary and limited within a few weeks after its implantation.Beyond that,there is no utility or advantages but only limitations just like foreign materials in patients' body.All of these problems can be solved with the use of fully bioabsorbable stent (BAS),which will disappear from the vessel wall after complete degradation and leave a "clean" vessel.Numerous BASs are currently undergoing pre-clinical and clinical trials.1'2 The purpose of the present study was to assess the short-term effects of a novel,fully bioabsorbable poly-L-lactic acid (PLLA)sirolimus-eluting stent (SES) made in China compared with a metallic durable polymer-coated sirolimus-eluting Cypher stent in healthy porcine coronary arteries.
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