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Progressive macular hypomelanosis with asymmetrically distributed lesions

摘要To the editor:A 28-year-old Chinese woman was referred for the evaluation of whitish macules.The macules firstly appeared in left upper back three years ago and then spread to left limb slowly but steadily in size.After the first gravidity at age of 26 years,the patient observed a marked acceleration of this process.She was previously diagnosed with pityriasis versicolor and was treated with ciclopirox cream and zinc pyfithione shampoo without improvement.There was no history of itching or dysaesthesia.The patient denied recreational sun exposure in past five years.When exposed to sunlight,the whitish macules did not change in the color whereas the non-affected skin became more tanned,thus the contrast against the whitish macules skin was remarkably intensified.There is no similar individual in her family.Skin findings of this patient consisted of scattered,partial confluent,non-scaly,well-defined,round or oval hypopigrnented macules which asymmetrically distributed on left upper back and left limb (Figure 1A and 1C),and no similar lesions on the other side of the body (Figure 1B).No signs of inflammation were present in these macules.

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作者单位 Institute of Dermatology & Department of Dermatology, First Hospital of Anhui Medical University, Hefei, Anhui 230032, China [1]
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DOI 10.3760/cma.j.issn.0366-6999.20131518
发布时间 2013-11-01(万方平台首次上网日期,不代表论文的发表时间)
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中华医学杂志(英文版)

中华医学杂志(英文版)

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