CRABP2 and FABP5 identified by 2D DIGE profiling are upregulated in human bladder cancer

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摘要Bladder cancer (BC) is the second most common malignancy of the human genitourinary tract,and is characterized by a high recurrence rate and expensive treatment) There is still no ideal biomarker for diagnosing or monitoring human BC.In the present study,we used proteomics analysis,including two-dimensional fluorescence difference gel electrophoresis (2D DIGE) and matrix-assisted laser desorption ionization time of flight/time of flight mass spectrometry (MALDI-TOF/TOF MS),to identify new potential protein markers of BC.

作者单位 Department of Urology ,First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, Zhejiang 310003, China ^[1] Department of Urology,First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, Zhejiang 310003, China ^[2] Department of Nephrology, Hangzhou Traditional Chinese Medical Hospital, Hangzhou, Zhejiang 310003, China ^[3] Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health; Key Lab of Organ Transplantation; Department of Hepatobiliary and Pancreatic Surgery,First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, Zhejiang 310003, China ^[4]

关键词 CRABP2 FABP5 2D DIGE biomarker bladder cancer

栏目名称

SHORT COMMUNICATION

DOI 10.3760/cma.j.issn.0366-6999.20130786

发布时间 2013-11-12

基金项目

grants from Major Program of Science and Technology Bureau of Zhejiang Province （2009C14015）

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