摘要Cardiac arrest (CA) is a major cause of death,with an estimated 300 000 cases of out-of-hospital CA reported in Europe and the United States each year.Advances in resuscitation techniques have improved survival such that approximately one-third of patients achieve return of spontaneous circulation (ROSC).Nonetheless,only between half and one-third of patients who have achieved ROSC survive until discharge.Current studies indicate that timely resuscitation and postresuscitation care,including targeted management of blood pressure,oxygen saturation (SpO2),partial pressure of carbon dioxide (PaCO2),blood glucose,and body temperature,have a major impact on survival and neurological outcomes in survivors of CA.13 However,most main factors influencing neurological outcomes remain unknown.