摘要Spinal muscular atrophy (SMA) is a genetic neuromuscular disorder characterized by progressive degeneration of the anterior horn cell leading to a lower motor neuron lesion.It is characterized by degeneration of alpha neurons in the anterior horn cells of the spinal cord leading to progressive muscle atrophy and premature death,usually from respiratory failure.1 There are four types according to the symptoms (Table 1).
作者单位Department of Anesthesiology, Pain Medicine & Critical Care Medicine ,Aviation General Hospital of China Medical University & Spinal Muscular Atrophy Lab, Beijing Institute of Translational Medicine, Chinese Academy of Sciences, Beijing 100012, China[1]Department of Gynaecology and Obstetrics ,Aviation General Hospital of China Medical University & Spinal Muscular Atrophy Lab, Beijing Institute of Translational Medicine, Chinese Academy of Sciences, Beijing 100012, China[2]