摘要To the editor:We present a case of cerebral venous thrombosis in an adult patient with nephrotic syndrome.A 42-year-old male was admitted to Peking University First Hospital complaining of a headache for 3 days followed by clumsiness of both hands and generalized seizures.A diagnosis of nephrotic syndrome (NS) was made 1 month ago,of which the pathology was minimal change disease (Figure 1 and 2).He was in remission and took prednisone 50 mg/d regularly.Upon physical examination,edema of bilateral lower limbs was noted,and he was comatose without other significant neurological signs.Urine protein excretion was 24.97 g/24 hours and serum albumin 26.7 g/L.Computed tomography venography of the head showed a suspicious filling defect in the superior sagittal sinus as well as subarachnoid hemorrhage.