摘要To the editor:Pemphigus herpetiformis (PH) is a rare form of pemphigus with distinctive clinical appearance of dermatitis herpetiformis and histological features of eosinophilic spongiosis.Treatment of PH is restricted to systemic steroids and immunosuppressants.Paradoxically,mortality and morbidity related to PH are more likely caused by side-effects associated with steroid treatment,such as hypertension and osteoporosis,rather than the disease itself.The combination use of minocycline and nicotinamide have been reported beneficial for patients with pemphigus vulgaris (PV),pemphigus vegetans (PVeg) and pemphigus foliaceus (PF).1,2 Here,we report a patient of PH who was successfully treated with a combination of minocycline and nicotinamide.