换一批摘要It is generally believed that genotype and adult lifestyle elements are primary risks of diabetes mellitus.However,increasing evidence demonstrates that early life malnutrition during the period of gestation and/or lactation may increase our susceptibility to some metabolic diseases in later life and the underlying mechanism is not very clear.Recently,epigenetics is hypothesized to be the important molecular basis of the imbalanced early life nutrition and glucose metabolism disorders.The fundamental mechanism is that early developmental nutrition can regulate epigenetic modifications of some genes associated with development and metabolism.
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DOI
10.3760/cma.j.issn.0366-6999.20141798
发布时间
2014-11-18（万方平台首次上网日期，不代表论文的发表时间）
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