Development of Crescentic Immunoglobulin A Nephritis and Multiple Autoantibodies in a Patient during Adalimumab Treatment for Rheumatoid Arthritis

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摘要To the Editor:Tumornecrosis factor-α (TNF-α) is a pro-inflammatory cytokine that plays a crucial role in the pathogenesis of rheumatoid arthritis (RA),while the advent ofanti-TNF-α agents brings better control and low side effects in RA.The most frequent side effects are infectious disease and drug-induced lupus.Herein,we present a case of Chinese man with a 10-year history of RA developing crescentic immunoglobulin A (IgA) nephritis and multiple autoantibodies during adalimumab treatment.

作者单位 Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing 100730, China ^[1] Renal Division, Department of Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China ^[2]

栏目名称 Correspondence

DOI 10.4103/0366-6999.164992

发布时间 2015-10-16

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