Unilateral Internal Carotid Artery Occlusion After Letrozole Treatment in a Postmenopausal Woman with Breast Cancer
摘要To the Editor: Letrozole, a third-generation aromatase inhibitor (AI), is a relatively newer class of endocrine agents used in hormone-receptor-positive breast cancer[1] Vascular thrombotic events, such as acute myocardial infarction and acute cerebral infarction, in patients with breast cancer after initiation of letrozole therapy have been documented in the literature.[2,3] However, the impact of this adjuvant endocrine therapy on increasing the risk of developing vascular thrombotic events has been a controversial issue.Here, we report a rare case of a woman with breast cancer developing unilateral internal carotid artery (ICA) occlusion after letrozole treatment.
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