摘要Primary central nervous system lymphoma (PCNSL) is an aggressive non-Hodgkin Lymphoma,most frequently diffuse large B-cell lymphoma in immunocompetent patients,which is confined to the central nervous system.[1] In the past two decades,its incidence has been steadily increasing.However,differential diagnosis,such as demyelinating disease,could be a challenge particularly in patients with atypical clinical symptoms and neurological imaging.Here,we described clinical presentation,imaging and pathological results of two cases of PCNSL and highlighted the importance of considering the possibility of PCNSL initially when cases were similar.
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