摘要INTRODUCTIONSevere acute pancreatitis (AP) remains a challenge in clinical practice,and there are no internationally agreed specific therapies,Severe AP typically presents with epigastric pain,abdominal distention,vomiting,and constipation at the early stage and is similar to the Yangming-Fushi syndrome of traditional Chinese medicine (TCM).The Chinese herbal ointment Liu-He-Dan (LHD) has been adapted for the treatment of AP with Yangming-Fushi syndrome externally on belly for many years in our hospital.However,the potential mechanism of LHD in the treatment of severeAP has not been elucidated.
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