Inhalation of Sevoflurane and Desflurane Can Not Affect QT Interval, Corrected QT, Tp-Te/QT or Tp-Te/JT in Children
摘要To the Editor:Sevoflurane and desflurane are the most common general anesthetics used in children.Previous study has shown that these agents can affect the electrocardiogram (ECG) markers,[1] leading to fatal ventricular arrhythmia.The followings were identified as useful indices for predicting and estimating the occurrence of a fatal arrhythmia:the interval between the peak and the end of T wave (Tp-Te),[2] the ratio of the Tp-Te interval to the QT interval ([Tp-Te/QT][3]),and the JT interval (JT),which is measured from the end of the QRS complex to Te.[4] The QT interval may be affected by sex and age.[5] However,little is known about the co-effect of the inhaled agent and sex on the corrected QT (QTc) and Tp-Te/QT and Tp-Te/JT ratios.
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