摘要Background:Identification of the proper femoral intramedullary (IM) access point is an important determinant of final implant position in IM-guided total knee arthroplasty (TKA).The aim of this study was to identify the optimal entry point in Chinese participants using a new three-dimensional method.Methods:A series of computed tomography scans of 44 femurs in Chinese participants from October 2014 to October 2015 were imported into Mimics 17.0 software to identify the optimal entry point.The apex of the intercondylar notch (AIN) was used as the reference bony anatomical landmark to identify the proper entry point to insert the IM rod.The statistical significance was calculated on the basis of a 5％ level (P ＜ 0.05) using the Student's t-test.Results:For the males,the average ideal entry point was 1.49 mm medial and 13.39 mm anterior to the AIN.The values were 1.77 mm medial and 15.29 mm anterior to the AIN in females.A significant difference was present between males and females (13.39 ± 2.46 mm vs.15.29 ±4 3.44 mm,t =2.124,P =0.040).When using the recommended location as the entry point for the IM rod,the mean potential error differed significantly from the femoral trochlear groove (the potential error of IM in males in coronal plane:0.93° ± 0.24° vs.1.27° ± 0.32°,t =-4.166,P ＜ 0.001;the potential error of IM in males in sagittal plane:1.40° ± 0.42° vs.2.79° ± 0.70°,t =-7.155,P ＜ 0.001;the potential error of IM in females in coronal plane:0.73° ± 0.28° vs.1.15° ± 0.35°,t =-3.940,P ＜ 0.001;and the potential error of IM in females in sagittal plane:1.48° ± 0.47° vs.2.76° ± 0.83°,t =-5.574,P ＜ 0.001).A significant difference was present between the recommended point and the point 10 mm anterior to the origin of the posterior cruciate ligament (the potential error of IM in males in coronal plane:0.93° ± 0.24° vs.1.53° ± 0.43°,t =-5.948,P ＜ 0.001;the potential error ofIM in males in sagittal plane:1.40° ± 0.42° vs.2.15° ± 0.75°,t =-3.152,P=0.003;the potential error of IM in females in coronal plane:0.73° ± 0.28° vs.1.28° ± 0.42°,t =-4.632,P ＜ 0.001;and the potential error ofIM in females in sagittal plane:1.48° ± 0.47° vs.2.40° ± 0.93°,t =-3.763,P =0.001).Conclusions:The technique described here is an innovative method for swift,easy,and accurate access to the medullary canal during TKA,and it can optimize the position and orientation of the prosthetic components in knee arthroplasty.