摘要Background:Many clinical studies over the past decade have indicated positive outcomes for patients treated with Dynesys dynamic stabilization for lumbar degenerative disease.However,long-term outcomes of Dynesys for lumbar spinal stenosis are rarely reported.The aim of this study was to analyze the long-term clinical and radiologic outcomes for patients with lumbar spinal stenosis treated with Dynesys stabilization.Methods:Thirty-eight patients with lumbar spinal stenosis were treated with Dynesys stabilization from July 2008 to March 2010.The minimal duration of follow-up was 72 months.The patients were divided into stenosis and spondylolisthesis groups according to degenerative spondylolisthesis.Clinical outcomes were evaluated using the Oswestry Disability Index (ODI) and visual analog scale (VAS).Radiographic evaluations included range of motion (ROM) and the disc heights of stabilized segments and the upper adjacent segments.We also evaluated the occurrence of radiographic and symptomatic adjacent segment degeneration (ASD).Results:There were 23 patients in stenosis group and 15 patients in spondylolisthesis group.The ODI scores were significantly improved at the final follow-up evaluation,as compared to the baseline values (16.1 ± 5.7 vs.57.2 ± 14.2,t =61.41,P ＜ 0.01).The VAS scores for back and leg pain were significantly improved from 4.82 ± 0.89 and 4.04 ± 0.82 preoperatively to 0.93 ± 0.61 and 0.54 ± 0.51 postoperatively (t =6.59,P ＜ 0.01,and t =5.91,P ＜ 0.01,respectively).There were no differences between the two groups with respect to VAS and ODI scores.The ROM of stabilized segments decreased significantly from 7.8° ± 2.4° to 4.5° ± 1.5° (t =7.18,P ＜ 0.05),while the upper adjacent segments increased significantly from 8.3° ± 2.4° to 10.4° ± 2.4° (t =2.87,P =0.01).The change in disc height of stabilized segments was not significant (11.9 ± 2.1 preoperatively vs.12.5 ± 1.5 postoperatively,t =1.43,P =0.15),whereas the decrease in disc height of the upper adjacent segments was significant (12.5 ± 2.0 preoperatively vs.11.0 ± 1.7 postoperatively,t =2.94,P =0.01).The occurrence of radiographic and symptomatic AS D was 16％ (6/38) and 3％ (1/38),respectively.Conclusions:Decompression and Dynesys stabilization for lumbar stenosis with or without spondylolisthesis showed good long-term clinical and radiographic results.Lumbar stenosis with or without Grade I spondylolisthesis,particularly in patients ＜60 years of age with mild-to-moderate lumbar disc degeneration,would be one of the main indications for the Dynesys system.