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Progresses in pharmaceutical and surgical management of premature ejaculation

摘要:

Objective:Premature ejaculation (PE) is regarded as one of the most common male sexual dysfunctions.This review introduced several pharmaceutical and surgical methods for the management of PE.The definition,etiology,behavioral,and psychological therapy of PE were also discussed.Data sources:"Premature," "ejaculation," or "sexual dysfuction" were used as the medical subject headings (MeSH) to obtain relevant articles before June 2019 on Pubmed,Google Scholar and CNKI.Most articles used were written in English and several Chinese articles were also cited.Study selection:Full-text articles of retrospective/prospective/randomized controlled trials were analyzed.Animal experiments and letters were excluded.Results:There are four PE sub-types:lifelong PE,acquired PE,natural variable PE,and subjective PE.Behavioral therapy,psychotherapy,medication,topical anesthetics,and surgery are currently used for the treatment of PE.However,all the above treatments have limitations.Therefore,novel ways should be investigated to more efficiently control PE.Conclusions:The pharmaceutical therapy that is currently being used in clinical practice for the management of PE is still the main choice globally due to its good efficacy.Surgery may be a choice for patients who are resistant to medication.However,it should be performed cautiously.

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作者单位: Department of Reproductive Medicine, Ningbo First Hospital, The Affiliated Hospital of Ningbo University, Ningbo, Zhejiang 315010, China [1] School of Medicine, Ningbo University, Ningbo, Zhejiang 315000, China [2] Translational Research Laboratory for Urology, The Key Laboratory of Ningbo City, Ningbo First Hospital, The Affiliated Hospital of Ningbo University, Ningbo, Zhejiang 315010,China [3] Translational Research Laboratory for Urology, The Key Laboratory of Ningbo City, Ningbo First Hospital, The Affiliated Hospital of Ningbo University, Ningbo, Zhejiang 315010,China;Department of Urology, Ningbo First Hospital, The Affiliated Hospital of Ningbo University, Ningbo, Zhejiang 315010, China [4]
期刊: 《中华医学杂志(英文版)》2019年132卷19期 2362-2372页 SCIMEDLINEISTICCSCDBP
栏目名称: Review Article
DOI: 10.1097/CM9.0000000000000433
发布时间: 2019-11-19
基金项目:
a grant from the Zhejiang Provincial Foundation for Medical and Health Sciences
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