Tumor-induced osteomalacia caused by a phosphaturic mesenchymal tumor of the femur

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摘要To the Editor:Tumor-induced osteomalacia (TIO) is an extremely rare paraneoplastic syndrome that is characterized by hypophosphatemia and hyperphosphaturia.[1] Since TIO was first described in 1947,more than 500 cases have been reported worldwide.[2,3] TIO is an acquired hypophosphatemic osteomalacia caused by decreased phosphorus reabsorption in the renal tubules and increased renal phosphorus excretion.

作者单位 Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China ^[1] Department of Endocrinology, Key Laboratory of Endocrinology, National Health and Family Planning Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China ^[2] Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China ^[3]

栏目名称 Correspondence

DOI 10.1097/CM9.0000000000000458

发布时间 2019-11-19

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