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Deep neural network-assisted computed tomography diagnosis of metastatic lymph nodes from gastric cancer

摘要Background: Artificial intelligence-assisted image recognition technology is currently able to detect the target area of an image and fetch information to make classifications according to target features.This study aimed to use deep neural networks for computed tomography(CT)diagnosis of perigastric metastatic lymph nodes(PGMLNs)to simulate the recognition of lymph nodes by radiologists,and to acquire more accurate identification results.Methods: A total of 1371 images of suspected lymph node metastasis from enhanced abdominal CT scans were identified and labeled by radiologists and were used with 18,780 original images for faster region-based convolutional neural networks(FR-CNN)deep learning.The identification results of 6000 random CT images from 100 gastric cancer patients by the FR-CNN were compared with results obtained from radiologists in terms of their identification accuracy.Similarly,1004 CT images with metastatic lymph nodes that had been post-operatively confirmed by pathological examination and 11,340 original images were used in the identification and learning processes described above.The same 6000 gastric cancer CT images were used for the verification,according to which the diagnosis results were analyzed.Results: In the initial group,precision-recall curves were generated based on the precision rates,the recall rates of nodule classes of the training set and the validation set; the mean average precision(mAP)value was 0.5019.To verify,the results of the initial learning group,the receiver operating characteristic curves was generated,and the corresponding area under the curve(AUC)value was calculated as 0.8995.After the second phase of precise learning,all the indicators were improved,and the mAP and AUC values were 0.7801 and 0.9541,respectively.Conclusion: Through deep learning,FR-CNN achieved high judgment effectiveness and recognition accuracy for CT diagnosis of PGMLNs.

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作者单位 Department of General Surgery,The Affiliated Hospital of Qingdao University,Qingdao,Shandong 266555,China [1] Beihang University Qingdao Research Institute,Qingdao,Shandong 266100,China [2] Department of Medical Administration,The Affiliated Hospital of Qingdao University,Qingdao,Shandong 266555,China [3] Department of Follow-up Center,The Affiliated Hospital of Qingdao University,Qingdao,Shandong 266555,China [4] Department of General Surgery,The Affiliated Hospital of Qingdao University,Qingdao,Shandong 266555,China;Shandong Key Laboratory of Digital Medicine and Computer Assisted Surgery,Qingdao,Shandong 266555,China [5]
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DOI 10.1097/CM9.0000000000000532
发布时间 2020-03-22
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中华医学杂志(英文版)

中华医学杂志(英文版)

2019年132卷23期

2804-2811页

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