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摘要本文首次报告国内由肠道病毒70型（EV70）及柯萨奇（Coxsackie）A24型病毒引起急性出血性结膜炎流行。从流行的不同时期收集的58份患者眼拭标本中分离到36株病毒，病毒鉴定表明，此次流行由EV70型病毒引起，发展为Coxsackie A24型病毒与EV70型病毒共同引起流行。血清抗体测定与病毒分离结果一致。

abstractsAn outbreak of acute hemorrhagic conjunctivitis (AHC) occurred in Guangzhou city from July to September in 1988. The eye swabs from the patients were collected in different periods of the epidemic. Thirty-six strains of AHC virus were isolated from 58 eye swabs of the patients. Twenty-three out of 31 virus isolates were identified as enterovirus 70 (EV70), and these specimens with EV70 strains were collected and isolated before 15 August. However four strains of Coxsackie virus A24 (Cox A24) were isolated from specimeus obtained in September. The serological study confirmed that the corresponding patients were infected with EV70 and/or Cox A24 viruses. It is concluded that the outbreak of AHC was initially caused by EV70 and then developed a mixed infection of EV70 and Cox A24. This mode of epidemic was found for the first time in China.