摘要目的 分析重型颅脑损伤后长期意识障碍患者的生存质量及体感诱发电位(SEP)分级. 方法 对47例重度颅脑损伤后意识障碍超过2周的患者进行清醒预测,选择5个预后因子即年龄、性别、受伤机制、去骨瓣减压手术、SEP表现方式对预后进行分析.生存质量以6个月后格拉斯哥预后评分(GOS)为标准进行判别. 结果 患者预后状态与SEP分级有明显相关性(P=0.024).SEP对预后的预测准确率为91.5%.患者的SEP分级为Ⅰ级时,44%(7/16)的患者预后良好;若患者的SEP分级为Ⅱ～Ⅲ级,则95%～100%的患者预后为重残、植物状态或死亡.结论 SEP分级可客观、准确地评估患者的预后及反映脑功能状态.

abstractsObjective To study prognosis and grading of somatosensory evoked potential(SEP)in long-term unconscious patients after severe traumatic brain injury(TBI).Methods Five prognostic factors including age,sex,injury mechanism,history of temporal craniotomy and SEP grading were selected and analyzed in 47 patients after severe TBI with a duration of unconsciousness longer than two weeks.The prognosis was judged by Glasgow Outcome Scale.Results Prognosis was closely associated with SEP grading(P=0.024).The accuracy of SEP in assessing the prognosis was 91.5%.About 95%-100% of patients with SEP at grade Ⅲ-Ⅲ ended up with severe disability,persistent vegetative state or death.However,43.75% of patients with SEP at grade Ⅰ had good prognoses.Conclusions The SEP grading can objectively and accurately evaluate patients' prognosis and demonstrate the brain function.