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骨关节炎（osteoarthritis，OA）是一种常见的关节退行性疾病，给患者、家庭和社会造成了沉重的负担。规范化的OA诊断及治疗对临床工作和社会发展均有重要意义。指南更新由中华医学会骨科学分会关节外科学组、中国医师协会骨科医师分会骨关节炎学组、国家老年疾病临床医学研究中心（湘雅医院）和中华骨科杂志编辑部牵头发起，采用推荐意见分级的评估、制订及评价（Grading of Recommendations Assessment, Development and Evaluation，GRADE）分级体系和国际实践指南报告标准（Reporting Items for Practice Guidelines in Healthcare，RIGHT）遴选出骨科医生最为关注的15个临床问题，最终形成30条循证医学推荐意见，旨在提高OA诊疗的科学性并最终提升以患者为中心的医疗服务质量。

Osteoarthritis (OA) is a highly prevalent degenerative joint disease representing a substantial burden for affected individuals, families, and the society. Thus, standardized diagnosis and treatment of OA are of great significance to clinical work and social development. This guideline update was initiated by the Joint Surgery Branch of the Chinese Orthopaedic Association, the Subspecialty Group of Osteoarthritis, Chinese Association of Orthopaedic Surgeons, the National Clinical Research Center for Geriatric Disorders (Xiangya Hospital) and the editorial department of the Chinese Journal of Orthopaedics. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach and the Reporting Items for Practice Guidelines in Healthcare (RIGHT) checklist were adopted. Finally, 30 evidence-based recommendations were formulated based on 15 most concerned clinical problems among orthopaedic surgeons in China. This guideline is intended to improve the scientific nature of OA diagnosis and treatment and ultimately improve the quality of patient-centered medical services.