摘要比较了《丙型肝炎防治指南(2019年版)》和以往《丙型肝炎指南》的更新要点.介绍了新的术语.重点强调了世界卫生组织提出的目标——2030年消除病毒性肝炎的公共卫生威胁.在预防部分,将对高危人群进行丙型肝炎病毒感染筛查作为预防的首要手段,强调治疗就是预防.在治疗方面,首先推荐无干扰素的泛基因型方案.还介绍了我国自主研发的直接抗病毒药物,介绍了多个特殊人群的抗病毒治疗方案,包括肝硬化失代偿、慢性肾脏疾病、儿童和青少年、合并慢性肾脏损伤、肝移植前后、合并HBV感染、治疗失败人群、急性丙型肝炎等.介绍了简化的治疗监测流程,特别提到在我国西南地区流行的基因3型.

abstractsThe key points from the updated guideline of prevention and treatment for hepatitis C (2019 version) is compared with the previous hepatitis C guideline.A new terminology and the World Health Organization's goal of eliminating viral hepatitis as a public-health threat by 2030 are stressed.In the prevention section,the screening for hepatitis C virus infection in high-risk population is the primary means of prevention,emphasizing that treatment,is prevention.In the aspect of treatment,pangenotypic interferon-free scheme are initial recommendations.In addition,it also introduces our country independent research and development on direct-acting antiviral agents,and antiviral therapy schedule for many special populations,including decompensated liver cirrhosis,chronic kidney disease,children and adolescents combined with chronic kidney injury,HBV infection-before and after liver transplantation,treatment failure,and acute hepatitis C.A simplified on-treatment monitoring schedule,especially genotype 3 prevalent in Southwest part of our country is introduced.