检索历史 清除

乙醛脱氢酶2（ALDH2）是线粒体内一种重要的醛脱氢酶，具有清除乙醛和其他有毒醛类物质的作用，在肝脏中含量丰富，且与多种肝脏疾病的发生与发展密切相关。在人群中，ALDH2基因多态性对多种肝脏疾病的发生有重要影响。现主要综述近年来ALDH2在肝脏疾病中的研究进展，以期为临床预防和治疗提供理论依据。

Acetaldehyde dehydrogenase 2 (ALDH2) is an important kind of aldehyde dehydrogenase in mitochondria, which has the function of eliminating acetaldehyde and other toxic aldehydes substances. Furthermore, it is abundant in liver and is closely related to the occurrence and development of a variety of liver diseases. ALDH2 genetic polymorphisms plays an important role in the occurrence of a variety of liver diseases in the human population.This paper mainly reviews the research progress of ALDH2 in liver diseases in recent years, with a view to provide theoretical basis for clinical prevention and treatment.