摘要目的 观察高压氧(HBO)联合复方麝香注射液对弥漫性轴索损伤(DAI)患者促醒性治疗的临床效果.方法 经患者知情同意,并医院伦理委员会批准后,将68例DAI患者分成治疗组与对照组,每组34例,治疗组应用HBO联合复方麝香注射液治疗,对照组不给予HBO治疗,观察2组于伤后6个月作格拉斯哥预后评分(GOS)评估预后,同时比较2组患者的意识好转率.结果 HBO联合复方麝香注射液治疗组较对照组格拉斯哥昏迷量表(GCS)评分明显提高,疗效显著,且清醒率治疗组明显优于对照组,2组比较差异有统计学意义(P＜0.05).结论 HBO联合复方麝香注射液对弥漫性轴索损伤患者能加速苏醒,改善预后.

abstractsObjective To observe the clinical effect of hyperbaric oxygen (HBO) coupled with compound Shexiang injection on the patients with diffuse axon injury(DAI).Methods Sixty-eight cases of DAI were randomly divided into the treatment group and the control group,each consisting of 34 cases.The treatment group was treated with HBO coupled with compound Shexiang injection,while the control group was only given Shexiang injection.The clinical prognosis of the patients in the 2 groups was evaluated 6 months after injury by using GOS scores,and the recovery rates of consciousness were compared between the 2 groups.Results The GCS scores of the treatment group were increased markedly,as compared with those of the control group,and the rate of consciousness for the treatment group was obviously superior to that of the control group.Statistical significance could be noted,when comparisons were made between the 2 groups(P ＜ 0.05).Conclusions HBO coupled with compound Shexiang injection could arouse consciousness and prognosis of the patients with DAI.