摘要目的 观察早期高压氧治疗对注射玻尿酸所致皮肤缺血的疗效.方法 将注射玻尿酸所致皮肤缺血患者42例依据高压氧治疗情况分为2组:A组,给予常规治疗,部分患者高压氧治疗均于72 h后进行.B组,常规治疗基础上均于注射后72 h内行高压氧治疗.记录2组患者显效时间,并将高压氧开始治疗时间与显效时间行Pearson相关性分析;于注射后第10天比较2组患者的显效率.结果 A组平均显效时间为(13.2±2.8)d,B组平均显效时间为(11.0±3.1)d,2组比较差异有统计学意义(P<0.05).将高压氧开始治疗时间与显效时间行Pearson相关性分析,高压氧开始治疗时间与显效时间存在正相关(P<0.05);于第10天观察,A组显效率为28.57％,B组显效率为53.57％.结论 早期应用高压氧治疗对注射玻尿酸所致皮肤缺血的作用是肯定的,且高压氧治疗介入越早显效越快.

abstractsObjective To observe the therapeutic effects of hyperbaric oxygen ( HBO ) on skin ischemia induced by hyaluronic acid .Methods Forty-two patients with skin ischemia induced by hyaluronic acid were divided into 2 groups: The patients in group A were given routine treatment , and some patients received HBO therapy 72 hours later, while the patients in group B all received HBO therapy within 72 hours after injection of hyaluronic acid on the basis of routine therapy .Effectual time was recorded and compared between the patients of the 2 groups, and Pearson analysis was performed with respect to HBO implementation time and effectual time.Effectual rates were compared between the 2 groups, 10 days after injection of hyaluronic acid.Results The average effectual time of group A was (13.2 ±2.8)days, while that of group B was(11.0 ±3.1) days.Statistical significance could be noted when comparisons were made between them ( P<0.05).Results of Pearson analysis concerning HBO implementation time and effectual time indicated that there was a positive correlation between HBO implementation time and effectual time (P<0.05, r>0).Observation at day 10 showed that the effectual time of group A was 28.57％and that of group B was 53.57％.Conclusion Therapeutic effects of early HBO therapy on skin ischemia induced by hyaluronic acid injection was positive , and the earlier HBO intervention was made , the earlier the effectual time was .