摘要目的:研究中国南京持续性植物状态量表（CNPVSS）评估不同性别、年龄脑损伤患者意识状态的信度和效度，为该量表的临床应用提供科学的参考依据。方法:分析1 100例脑损伤后不同意识状态患者的CNPVSS评分结果，计算量表信度；对昏迷、植物状态/无反应觉醒综合征（VS/UWS）、微小意识状态（MCS）和意识清醒这4种意识状态进行效度分析。将男、女性患者各分为1～20岁、21～40岁、41～60岁和61～80岁等4个年龄亚组，分析在男、女性各4个年龄亚组患者中应用CNPVSS的信度和效度。结果:CNPVSS信度良好，Cronbach’s α系数为0.969；内部一致性良好（ P<0.001），各子项目得分与总分之间相关性良好（ P<0.001）；不同意识状态患者的CNPVSS总分分别为昏迷［1（1，2）分］、VS/UWS［2（2，3）分］、MCS［7（6，9）分］和意识清醒［19（16，20）分］，差异有统计学意义（ P<0.001）。不同性别年龄亚组的量表信度和效度均良好，与总体分析结果基本一致。 结论:CNPVSS是一个适合评估意识状态的量表，可用于80岁以下不同性别脑部损伤患者意识状态的量化分析。

abstractsObjective:To study the reliability and validity of the Chinese Nanjing persistent vegetative state scale（CNPVSS）in assessing the state of consciousness of brain-damaged patients in different gender and age subgroups，so as to provide a point of scientific reference for the clinical application of the scale.Methods:The reliability of the CNPVSS was calculated by statistically analyzing the CNPVSS scores of 1 100 patients in different states of consciousness after brain injury. The validity of the scale was analyzed by applying it to four states of consciousness：coma，vegetative state / unresponsive awakening syndrome（VS/UWS），minimally conscious state（MCS），and conscious wakefulness. The male and female patients were further divided into four age subgroups，respectively：1–20 years old，21–40 years old，41–60 years old，and 61–80 years old. The reliability and validity of CNPVSS scale in the eight groups were then evaluated.Results:The reliability of CNPVSS was good，and the Cronbach’s alpha coefficient was 0.969；the internal consistency was good（ P<0.001），and the correlation between the score of each item and the total score was statistically significant（ P<0.001）；the total scores of different states of consciousness：coma［1（1，2）］，VS / UWS［2（2，3）］，MCS［7（6，9）］，and conscious wakefulness［19（16，20）］，with statistically significant difference（ P<0.001）. The reliability and validity of the scale in different gender and age subgroups come out well，and the results were basically consistent with the overall analysis. Conclusion:CNPVSS is a good instrument for assessing the state of consciousness，which can be used for quantitative analysis of consciousness states of brain-damaged patients under 80 of different gender.