摘要目的 了解福州市20岁以上人群阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患病率及危险因素情况,为该病防治及开展前瞻性研究提供依据和基线资料.方法 采用随机整群抽样的方法对福州市五区部分20岁以上常住居民5500名进行入户调查;随机抽取打鼾≥13级315名、打鼾2级100名被调查者,进行整夜多导睡眠呼吸监测,推算人群中OSAHS的患病率;并对OSAHS发生进行相关危险因素分析.结果 实际完成调查人数4595名,应答率83.55%,有效问卷4286份,有效率93.28%;习惯性打鼾606名(14.14%),以呼吸暂停低通气指数(AHI)≥5次/h加Epworth嗜睡量表评分≥9分为标准,推算人群中OSAHS患病率为4.78%;多元逐步回归分析发现年龄、吸烟量、打鼾家族史、颈围、腰围及上气道异常是OSAHS发生的危险因素.结论 鼾症、OSAHS发生率高,应根据其在福州市流行特点制定相应防治策略,降低OSAHS发生中可变危险因素的作用,使其患病率及危害降到最低.

abstractsObjective To investigate the prevalence and risk factors of obstructive sleep apneahypopnea syndrome (OSAHS) in adults aged over 20 years in Fuzhou city, there fore to provide epidemiological data for Prevention and treatment of the disease, and establishing a data base for prospective study. Methods A total of 5500 subjects were derived from a random and cluster sampling of the population in 5 districts of Fuzhou city. They were asked to answer the questions from a questionnaire at home. According to the degree of snoring, 315 subjects with a snoring score≥3 degree and 100 subjects with a snoring score=2 degree were selected at random to undergo polysomnography for a whole night. The prevalence of the disease was estimated and the risk factors for OSAHS were analyzed. Results 4595 subjects(83.55%) responded, and validated questionnaires were obtained from 4286 subjects (effective power 93.28%); of whom 606 (14.14%) subjects had habitual snoring. The estimated prevalence of OSAHS defined by apnea-hypopnea index (AHI) ≥5 and Epworth sleepiness scale (ESS) ≥9 was 4.78%. Multivariate analysis revealed that age, smoking, family snoring, neck-circumference, waist circumference, and abnormality of the upper airway were significant risk factors for OSAHS. Conclusions The estimated prevalences of snoring and OSAHS in adults aged over 20 years in Fuzhou city was high. Strategies based on the epidemiological data in Fuzhou city are needed to cut down the prevalence and harm of OSAHS by controling modifiable risk factors.