摘要目的 探讨经气道人体白蛋白泡沫定位肺漏气支气管的方法,并评价其效果及安全性.方法 29例气胸患者,在纤维支气管镜直视下,人体白蛋白泡沫靶支气管内注射,定位肺漏气所属支气管.结果 29例患者肺漏气支气管均定位成功,从泡沫注射至确定肺漏气支气管定位所需平均时间为(4.0±1.2)min,20%人体白蛋白用量平均(8.0±2.6)ml/例.医用生物蛋白胶封堵成功21例,α-氰基丙烯酸酯封堵成功8例.并发症:剧烈咳嗽6例,发热和胸腔出血各4例,胸痛1例.结论 人体白蛋白泡沫靶支气管内注射是一种操作简单、价格低廉、安全和有效的肺破裂支气管定位的方法.

abstractsObjective To evaluate the efficacy and safety of a new method to determine the bronchus for air leakage in pneumothorax by injection of human albumin foam.Methods In 29 cases with pneumothorax,the bronchus responsible for air leakage was localized by injecting foam of human albumin into target bronchus under direct view of bronehoscopy.Results The bronchus for air leakage was successfully localized in all the 29 cases of pneumothorax.The average time for locating(from injection of the foam to the localization of the bronchus)was(4.0±1.2)min.and the average amount of 20%human albumin used was(8.0±2.6)ml for each patient.The air leakage Was treated accordingly,and occlusion by fibrin glue was successfully carried out in 21 cases and by OB glue in 8 csses.Severe couth was noted in 6,fever in 4,thoracic bleeding in 4 cases,and chest pain in 1 case.Conclusion Injection of human albumin foam into target bronchus under bmnchoseopy was a simple,safe and effective method for the localization of the bronchus for air leakage in pneumothorax.