摘要本文从方法学角度解读本期“慢性阻塞性肺疾病患者流感/肺炎疫苗接种状况及影响因素：真实世界的横断面研究”一文的优点和不足。强调选题紧密结合临床问题和需求的重要性，合理可行的研究方法为临床研究保驾护航。提出在“一篇论文研究回答一个问题”的框架下提高研究和论文撰写内在质量的必要性和实操性，分析影响因素研究的目标任务及合理的技术路线，强调临床研究方法为回答临床问题和科学问题服务。

abstractsThe advantages and disadvantages of the article "influenza/pneumonia vaccination status and influencing factors in patients with chronic obstructive pulmonary disease: a real-world cross-sectional study" were interpreted by methodological perspective. The importance of topic selection closely combined with clinical problems and needs was emphasized, and reasonable and feasible research methods to escort clinical research. This paper puts forward the necessity and practicality of improving the internal quality of research and paper writing under the framework of "one paper research and answering one question", analyzes the objectives, tasks and reasonable technical route of influencing factor research, and emphasizes that clinical research methods serve to answer clinical and scientific questions.