摘要目的:检索、评价和总结新型冠状病毒感染（COVID-19）引起的低氧血症患者清醒俯卧位治疗的最佳证据，旨在指导护理人员规范实施COVID-19患者清醒俯卧位治疗。方法:系统检索UpToDate、BMJ Best Practice、JBI循证卫生保健中心数据库、美国重症监护护士协会、英国重症监护协会、欧洲呼吸学会、世界卫生组织网站、Cochrane Library、PubMed、中国知网、万方等数据库，对检索到的文献进行质量评价和证据提取。结果:共纳入10篇文献，包括1篇专题证据汇总、1篇指南、2篇系统评价、3篇随机对照试验、3篇专家共识，总结了组织管理与培训、风险评估、操作准备、实施要点、风险控制5个方面共30条最佳证据。结论:清醒俯卧位治疗有利于COVID-19患者改善低氧血症，且简单易行。医疗机构应基于循证证据构建清醒俯卧位治疗的护理管理制度、操作规范、最佳实践等，以提高该类患者的护理管理质量。

abstractsObjective:To retrieve, evaluate, and summarize the best evidence for the treatment of hypoxemia in patients with COVID-19 infection using the awake prone positioning, with the aim of guiding healthcare professionals in the standardized implementation of this therapy.Methods:A systematic search was conducted in databases including UpToDate, BMJ Best Practice, JBI Evidence-Based Healthcare Center, American Association of Critical-Care Nurses, Intensive Care Society, European Respiratory Society, World Health Organization website, Cochrane Library, PubMed, China National Knowledge Infrastructure (CNKI), and Wanfang. The retrieved literature was subjected to quality assessment and evidence extraction.Results:A total of ten publications were included, consisting of one thematic evidence summary, one guideline, two systematic reviews, three randomized controlled trials, and three expert consensus statements. This summary synthesizes thirty key pieces of evidence in five categories: organizational management and training, risk assessment, preparatory operations, implementation key points, and risk control.Conclusions:Awake prone positioning is beneficial for improving hypoxemia in patients with COVID-19 and is easy to implement. Medical institutions should develop nursing management systems, operational standards, and best practices for awake prone positioning based on evidence-based evidence in order to improve the quality of care management for such patients.