摘要目的 探讨青少年空腹血糖受损(wG)与体脂分布的关系.方法 通过分层整群随机抽样,测定3874例13～18岁青少年身高、体重、腰围、臀围和空腹血糖(FPG)水平,通过问卷调查了解其父母糖尿病患病情况.根据F1PG水平,分为空腹血糖正常组(FPG＜5.6 mmol/L,n=3738)和空腹血糖受损组(5.6 mmol/L≤FPG＜7.0 mmol/L,n=136).结果 两组间各体脂指标比较,应用协方差分析校正性别、年龄后,空腹血糖受损组体重指数、腰围、腰围/身高比和腰臀比均高于空腹血糖正常组,组间比较差异有统计学意义(P＜0.05).应用偏相关分析校正年龄、性别后,BMI、腰围、腰臀比及腰围/身高比均与FPG呈正相关(P＜0.05),其中腰围/身高比的r'值最大(r'=0.0925).对FPG的多元线性回归分析,最佳模型引入年龄(β=-0.102,P＜0.05)、糖尿病家族史(β=0.186,P＜0.05)和腰围/身高比(β=0.842,P＜0.05).结论 中心性肥胖与青少年空腹血糖受损关系密切,腰围/身高比是描述青少年中心性肥胖的有效指标,是青少年空腹血糖受损的独立危险因素.

abstractsObjective To investigate the relationship between impaired fasting glucose(IFG) and the distribution of body fat in adolescents.Methods Stratified cluster sampling was used to select 3874 adolescents aged 13-18 years for this cress-sectional study.Measurements included height,weight,waist circumference,hip circumference and fasting plasma glucose (FPG).Family history of diabetes was determined by using a serf-administered questionnaire.Participants were divided into normal fasting glucose group(FPG＜5.6 mmol/L,n=3738) and impaired fasting glucose group (5.6 mmol/L≤FPG ＜ 7.0 mmoL/L,n=136) according to their FPG levels. Results (1) After adjusting for age and sex using covariance analysis,the impaired fasting glucose group showed increased levels of body mass index,weight circumference,waist/hip ratio,waist/height ratio,as compared to the normal fasting glucose group (P＜ 0.05).(2) After the age and gender were adjusted,body mass index,weight circumference,waist/hip ratio and waist/height ratio were positively correlated with FPG level (P＜0.05).Among the partial relation coefficients, that between waist/height ratio and FPG(r'=0.0925) was the highest (3) In multiple regression analyses,age (β=-0.102,P＜0.05),family history of diabetes (β=0.186,P＜0.05) and waist/height ratio (β=0.842,P＜0.05) were consistently associated with FPG.Conclusion Central obesity was an important predictor of IFG in adolescents.Waist/height ratio may be an useful index of central obesity and an important predictor of IFG in adolescents.