摘要目的 评估体检人群心理健康状况,探索心理指标与部分生理指标的相关性,筛选影响焦虑、抑郁的生理相关因素.方法 以3885例体检人群为研究对象,采用焦虑自评量表、抑郁自评量表、症状自评量表评估心理状况,选取体质指数(BMI)、收缩压(SBP)、舒张压(DBP)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、血清游离三碘甲腺原氨酸(FT3)、血清游离甲状腺素(FT4)、促甲状腺激素(TSH)为研究的生理指标.用Pearson相关性分析研究心理指标与生理指标的相关性；Logistic回归分析筛选影响焦虑、抑郁的生理相关因素.结果 体检人群女性焦虑、抑郁阳性率高于男性；小学及以下文化程度的人群焦虑、抑郁阳性率最高,随着学历的增高,焦虑阳性率逐渐降低.焦虑、抑郁评分与BMI、SBP、DBP、FT3、FT4之间存在负相关(r=-0.037 ～-0.092;P＜0.05).Logistic 回归分析提示LDL-C、FT3、FT4与抑郁评分有关,而SBP、FT3、FT4与焦虑评分有关.结论 体检人群中,焦虑、抑郁情绪与性别、学历有关,且SBP、FT3、FT4对焦虑情绪发生有保护作用,而LDL-C、FT3、FT4对抑郁情绪发生有保护作用.

abstractsObjective To investigate the relationship between mental status and some physical indicators,so as to identify the influencing factors of anxiety and depression in health check-up populations.Methods A total of 3885 health check-up adults enrolled in this investigation.Self-rating anxiety scale (SAS),self-rating depression scale (SDS),and Symptom Checklist 90 (SCL90) were used to evaluate mental health of the participants.Physical indicators,including body mass index (BMI),systolic blood pressure (SBP),diastolic blood pressure (DBP),triglyceride (TG),low-density lipoprotein cholesterol (LDL-C),serum free three iodine armour gland original acid (FT5),serum free thyroxine (FT4),and thyroid-stimulating hormone (TSH),were retrospectively reviewed.Pearson correlation analysis was used to assess the relationship between mental health and physical signs,and the Logistic regression analysis was performed to confirm the influencing factors of anxiety and depression.Results Increased prevalence of anxiety and depression was found in females or those with lower education level.For the health check-up populations,anxiety and depression were negatively correlated to BMI,SBP,DBP,LDL-C,FT3 and FT4.In Logistic regression analysis,LDL-C,FT3 and FT4 were related to SDS score,while SBP,FT3,and FT4 were related to SAS score.Conclusion Our data suggest that emotion could be affected by gender and education level; SBP,LDL-C,FT3,and FT4 may be protective factors of anxiety and depression.