营养干预对老年人肌肉蛋白合成的影响:系统综述
Effect of nutritional intervention on muscle protein synthesis in elderly people: a systematic review
摘要肌肉衰减征是年龄相关的进行性和广泛性骨骼肌质量及力量下降,并由此导致身体残疾、生活质量下降及感染和死亡风险增高等不良结局的综合征.营养素缺乏特别是蛋白质摄入不足可导致肌肉蛋白合成受阻,加速老年性肌肉衰减征发展进程.增龄性肌肉质量的丢失及肌力减退成为老年人主要的卫生问题.本文通过检索国内外有关营养干预对老年人肌肉蛋白合成及肌肉功能影响的文献,探讨不同营养干预对老年人肌肉蛋白合成及肌肉功能的影响.
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abstractsSarcopenia is a syndrome characterized by progressive and generalised loss of skeletal muscle mass and strength with a risk of adverse outcomes such as physical disability, poor quality of life and increasing risk of infection and mortality. Inadequate intake of nutrients (especially protein) might block muscle protein synthesis, and accelerate age-related sarcopenia progress. Age-related decline in skeletal muscle mass as well as muscle functions has been regarded as major health issues in elderly people. The domestic and foreign literature related to impact of nutritional intervention on muscle protein synthesis and muscle functions in elderly people were retrieved to evaluate the effect of nutritional intervention on muscle protein synthesis and muscle functions in elderly people.
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