摘要目的:比较脑血流动力学指标（CVHI）与改良弗莱明翰卒中风险评估（FSP）量表预测体检人群卒中的风险。方法:以2019年1月至2020年1月在江苏省人民医院健康管理中心的1 049例体检人群为研究对象，分析CVHI积分值、改良FSP量表与卒中危险因素相关性，并采用多因素Logistic回归分析评估CVHI分级、高血压病、糖尿病、吸烟史等对通过改良FSP量表评估的10年卒中风险的影响。结果:1049例体检人群中，CVHI评分<75分者163例（15.54%），改良FSP量表评估的10年卒中风险概率≥6%者202例（19.26%）。CVHI积分值与改良FSP量表评分呈负相关（ r=-0.284， P<0.001），多因素回归分析发现CVHI分级、高血压病、糖尿病、吸烟史是10年卒中风险预测的独立影响因素。 结论:CVHI预测体检人群卒中风险比例低于改良FSP量表，两者联合可有效预测卒中风险。

abstractsObjective:To compare cerebral vascular hemodynamic indexes (CVHI) and revised Framingham stroke risk profile (FSP) in predicting the risk of stroke among physical examiners.Methods:A total of 1 049 individuals were enrolled from the Health Management Center, Jiangsu Province Hospital during January 2019 and January 2020. Correlation analysis was carried out to confirm the correlations of risk factors of stroke with CVHI accumulative score and FSP. Multivariate logistic regression analysis was performed to evaluate the influence of CVHI classification, hypertension, diabetes and smoking on the 10-year risk of stroke evaluated by FSP.Results:In this study, the number of people whose CVHI accumulative score was less than 75 was 163 (15.54%) and the number of people whose 10-year probabilities of stroke was greater than or equal to 6% was 202 (19.26%). The CVHI accumulative score was negatively related with FSP ( r=-0.284, P<0.001). The result demonstrated that the CVHI classification, hypertension, diabetes and smoking were independent predictors for the 10-year risk of stroke evaluated by FSP. Conclusions:The proportion of individuals with stroke risk in medical examination population evaluated by CVHI is lower than by FSP. Combination of CVHI and FSP can effectively predict the risk of stroke among physical examiners.