摘要目的:比较锥形束CT图像与病理切片中缺牙区牙槽嵴顶骨皮质厚度（cortical bone thickness，CBT）的差异，探讨锥形束CT用于评估颌骨后牙区CBT的可行性。方法:回顾性纳入2019年6至12月就诊于中国科学技术大学附属第一医院·安徽省立医院口腔医学中心的后牙牙缺失患者60例，其中男性23例，女性37例，年龄（43.8±1.7）岁，缺牙区内共取出骨块63块。术前将患者锥形束CT图像导入口腔种植导航系统，设计完成后在测量界面中测量拟种植区的牙槽嵴顶CBT（锥形束CT图像组）。术中获取目标骨块制成切片，厚度0.4 μm，用Case Viewer软件测量切片中的CBT（病理图像组）。采用配对 t检验比较锥形束CT影像和病理图片中颌骨后牙区牙槽嵴顶CBT间的差异。 结果:病理图像组测得的骨皮质厚度在后牙区、上颌后牙区、下颌后牙区分别为（1.20±0.75）、（0.68±0.46）和（1.48±0.77）mm；锥形束CT图像组测得的CBT在后牙区、上颌后牙区、下颌后牙区分别为（1.14±0.77）、（0.64±0.24）和（1.41±0.83）mm，两组相同位置测量结果差异均无统计学意义（ P>0.05）。 结论:锥形束CT可用于颌骨骨皮质厚度的分析，且准确度较高。

abstractsObjective:To investigate the feasibility of cone-beam CT (CBCT) in evaluating the thickness of cortical bone in jaw bone.Methods:Sixty patients [twenty-three for males and forty-seven for females, at an average age of (43.8±1.7) years] from Center of Stomatology, The First Affiliated Hospital of USTC & Anhui Provincial Hospital with 63 operational regions were included in the present study. Totally 63 bone sections from these areas were all selected at last. Case Viewer and oral dynamic system were used for the measurements in sections and CBCT graphs of the cortical bone thicknesses at alveolar ridges. Paired samples t test was performed to compare the difference between CBCT measurement and Case Viewer measurement. Results:The cortical bone thicknesses measured by Case Viewer were (1.20±0.75), (0.68±0.46) and (1.48±0.77) mm in the posterior, maxillary posterior and mandibular posterior areas, respectively. The cortical bone thicknesses measured by dynamic navigation software were (1.14±0.77), (0.64±0.24) and (1.41±0.83) mm in the posterior, maxillary posterior and mandibular posterior areas, respectively. There were no significant differences between either the two methods or the different areas ( P>0.05). Conclusions:CBCT would be a useful equipment for the analysis of cortical bone thickness with a reliable and convincible accuracy.