沙眼衣原体感染与输卵管妊娠关系的Meta分析
Meta-analysis for correlation of Chlamydia trachomatis infections with tubal pregnancy
摘要目的 探讨沙眼衣原体感染与输卵管妊娠的关系.方法 制定原始文献的检索策略、纳入标准和排除标准,在中国学术期刊数据库、万方数据库和中文科技期刊数据库上联合检索1998-2007年国内专业期刊发表的论文.应用RevMan 4.2软件对沙眼衣原体感染与输卵管妊娠关系的相关文献进行Meta分析,以比值比(OR)及其95%可信区间(95%CI)为效应尺度.结果共检索到相关文献35篇,对符合纳入标准的16篇进行Meta分析.宫颈沙眼衣原体感染与输卵管妊娠组关系Meta分析的合并OR值为7.14(95%CI:5.20-9.80);输卵管组织沙眼衣原体感染与输卵管妊娠组关系Meta分析的合并OR值为6.50(95%CI:4.52-9.34).结论 输卵管妊娠的发生与沙眼衣原体感染密切相关.
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abstractsObjective To investigate the correlation of Chlamydia trachomatis (Ct) infection with tubal pregnancy by Meta-analysis. Methods Eligible literatures were searched from Chinese websites cnki,wanfangdata and eqvip from 1998 to 2007. Meta-analysis was conducted for the correlation of Ct infection with tubal pregnancy by software RevMan 4.2, and the results were expressed as odds ratio (OR) and 95% confidence intervals (95% CI). Results Thirty-five articles were retrieved, of which 16 were included in the Meta-analysis. The combined ORs of Ct infections in cervix uteri and in uterine tube to tubal pregnancy were7.14 (95% CI: 5.20-9.80) and6.50 (95% CI: 4.52-9.34), respectively. Conclusions There are significant correlation between Chlamydia trachomatis infection and tubal pregnancy.
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