摘要目的:探讨中老年男性健康体检人群吸烟与血尿酸(SUA)的关系。方法:横断面研究，选取2014年1月至2015年6月在江苏省太湖疗养院健康体检的26701例中老年男性为研究对象。采用问卷调查、体格检查和血生化指标检测等，分析吸烟状态与SUA的关系。结果:随年龄增长SUA呈下降趋势( F＝7.38， P＝0.000)；三组人群中少量吸烟组最高，现在吸烟组低于不吸烟和少量吸烟组( P＝0.000、0.005)。将SUA按四分位后：不吸烟组最高分位组(41.5%)高于最低分位组(38.4%)( χ2＝12.266， P＝0.000)；现在吸烟组最高分位组(54.9%)低于最低分位组(58.4%)( χ2＝7.049， P＝0.008)。与不吸烟组相比：现在吸烟组HUA患病率较低( OR＝0.872，95% CI：0.821～0.927， P＝0.000)；少量吸烟组HUA患病率较高( OR＝1.194，95% CI：1.013～1.408， P＝0.035)。 结论:与不吸烟组HUA患病率相比，现在吸烟人群HUA患病率较低，少量吸烟人群HUA患病率较高。

abstractsObjective:To explore the correlation between different smoking status and serum uric acid(SUA)in a middle-aged male in health check-up population.Methods:In this cross-sectional study, a total of 26701 middle-aged men who underwent health check-up in Taihu Sanatorium of Jiangsu Province from January 2014 to June 2015 were studied.The correlation between smoking status and SUA was analyzed by questionnaires, physical examination and serum biochemical assay.Smoking state was divided into no smoking, a occasional smoking and smoking groups.Results:With the increase of age, there was a downward trend of SUA( F=7.38, P=0.000). Among the three smoking groups, the group with occasional smoking had the highest level of SUA.The smoking group had lower level of SUA than the non-smoking group and occasional smoking group( P=0.000 and 0.005). In the non-smoking group, the fourth quartile of SUA(41.5%)had a higher percentage than that in first quartile of SUA(38.4%)( χ2=12.266, P=0.000). In the smoking group, the fourth quartile of SUA(54.9%)had lower percentage than that in the first quartile of SUA(58.4%)( χ2=7.049, P=0.008). Compared with the non-smoking group, the prevalence of hyperuricemia(HUA)in smoking group was lower( OR=0.872, 95% CI: 0.821~0.927, P=0.000), the prevalence of HUA in occasional smoking group was higher( OR=1.194, 95% CI: 1.013~1.408, P=0.035). Conclusions:As compared with the non-smoking group, the prevalence of HUA is lower in smoking group and is higher in occasional smoking group.