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目的 了解目前接受艾滋病抗病毒治疗患者中抑郁症的患病率,初步探索影响抑郁症产生的因素.方法 2015年6-12月对长沙市传染病医院艾滋病门诊接受艾滋病抗病毒治疗的180例患者开展横断面研究,采用问卷调查的方法评估患者合并抑郁症的情况.利用宗氏抑郁自评量表(SDS)筛查调查对象的抑郁症状(SDS得分≥50分),应用心理疾病专家诊断系统(心理CT)确诊是否患抑郁症,并用logistic回归分析影响抑郁症产生的因素.结果 初筛检出有抑郁症状者48例(26.67％),确诊抑郁症者33例(18.33％).多因素分析,艾滋病相关羞辱和歧视状况量表得分20 ～ 40分(OR=0.093,95％CI:0.020 ～ 0.431)是接受艾滋病抗病毒治疗患者抑郁症形成的保护因素,独居(OR=5.062,95％CI:1.626～ 15.764)、近3个月出现艾滋病相关的疾病(0R=3.778,95％CI:1.113～12.826)是接受艾滋病抗病毒治疗患者抑郁症形成的危险因素.结论 接受艾滋病抗病毒治疗患者抑郁症患病率应该引起关注,临床应加大对艾滋病患者的心理关怀.

Objective To understand the prevalence of depression in HIV/AIDS patients who are receiving highly active antiretroviral therapy (HAART),and identify the influencing factors for depression.Methods A total of 180 HIV/AIDS outpatients receiving HAART were recruited in a cross-sectional survey at the first hospital of Changsha from June to December 2015.The SDS questionnaire (SDS score≥50) was used to screen depression patients and psychological CT was used to confirm the depression.The influencing factors were identified through multivariate logistic analysis.Results Forty eight patients showed depressive symptoms in preliminary screening (26.67％),and 33 patients were diagnosed with depression (18.33％).HIV/AIDS related stigma and discrimination scale score 20-40 (0R=0.093,95％CI:0.020-0.43 1) was the protective factors.Living alone (0R=5.062,95％CI:1.626-15.764),HIV related diseases in recent three months (OR=3.778,95％ CI:1.113-12.826) were the risk factors.Conclusion More attention should be paid to the depression in HIV/AIDS patients receiving HAART.The mental health care for these patients needs to be improved in clinic practice.