摘要目的:探讨腹膜后节细胞神经瘤的临床诊治方法及疗效。方法:回顾性分析2015年4月至2022年5月北京大学国际医院收治的32例腹膜后节细胞神经瘤的临床资料，探讨其临床特点、手术疗效及预后。结果:32例腹膜后节细胞神经瘤中无明显临床症状17例，腹胀、腹痛7例，腰背部疼痛6例，腹部包块2例。18例位于肾上腺及肾区附近，11例位于肾下方脊柱两侧，3例位于盆腔。28例为单发肿瘤，4例为多发肿瘤，12例包绕大血管。手术R 0或R 1切除共27例，R 2切除5例，联合脏器切除6例，采用分块切除8例。肿瘤平均最大直径（13.2±4.9）cm，术中中位出血量为500 ml（50~6 000 ml），术后发生并发症6例。包绕血管的肿瘤组与未包绕血管的肿瘤组在年龄、出血量、R 2切除率、分块切除比例方面差异均有统计学意义（ t=2.44， P=0.021； Z=2.37， P=0.018； χ2=4.57， P=0.033； χ2=11.38， P=0.001）。R 0或R 1切除的患者无复发。 结论:腹膜后节细胞神经瘤完整切除的患者预后良好，包绕血管的肿瘤手术难度大，导致不能完整切除。

abstractsObjective:To explore the clinical diagnosis and treatment methods and curative effect of retroperitoneal ganglioneuromaMethods:The clinical data of 32 cases of retroperitoneal ganglioneuroma admitted to Peking University International Hospital from Apr 2015 to May 2022 were retrospectively analyzed, and their clinical characteristics, surgical efficacy and prognosis were discussed.Results:Of the 32 patients with retroperitoneal ganglioneuroma, 17 had no obvious clinical symptoms, 7 complained abdominal distension and pain, 6 had lower back pain, and 2 had abdominal mass. Tumors were located near the adrenal and renal regions in 18 cases, on both sides of the spine below the kidneys in 11 cases, and in the pelvis in 3 cases. tumors were single in 28 cases, multiple in 4 cases.Tumors were surrounded by major blood vessels in 12 cases. R 0 or R 1 resection was carried out in 27 cases, and palliative R 2 resection in 5 cases, combined organ resection in 6 cases, and piecemed resection in 8 cases. The maximum tumor diameter was (13.2±4.9)cm, the intraoperative blood loss was 500 (50-6 000 ml), and 6 cases suffered from major postoperative complications. Between patients with tumors encircling and encroaching major blood vessels or not, there were significant differences in age, intraoperative blood loss, R 2 resection rate, and pieceneal resection rate between the two groups ( t=2.44, P=0.021; Z=2.37, P=0.018; χ2=4.57, P=0.033; χ2=11.38, P=0.001). There was no recurrence in patients with R 0 or R 1 resection. Conclusions:The prognosis of complete resection of retroperitoneal ganglioneuroma is good .Major blood vessels encroachment of the tumor often leads to incomplente (R 2) resection.