摘要对1例乙型肝炎肝硬变患者实施原位肝移植术,使用UW液保存供体肝脏6小时,术中采用静脉一静脉转流.术后应用大剂量甲基强的松龙和标准剂量的环孢素A(CsA)进行免疫抑制治疗,对术后迟发性急性排斥反应使用甲基强的松龙冲击治疗,根据血中CsA浓度调整CsA用量,术后第6个月时HBsAg再度转为阳性,但目前患者一般情况良好,生活自理,肝脏功能正常.认为乙型肝炎患者施行肝移植时必须配合相应的治疗,以预防肝炎复发.

abstractsAn orthotopic liver transpIantation was successfully performed on an hepatitis Brelated cirrhotic patient with portal hypertension.The donor liver was preserved with UW solution for 6 hours.The venovenous bypass was introduced in the operation.The triple-drug immunosuppression was used.The episode of late acute rejection was treated with high dose steroid.The hepatitis was recurred 6 months postoperatively.However,the patient is still in a good with normal liver function.It is suggested that liver transplantation in patient with hepatitis B should be performed under the protection of adjuvant therapy to prevent the recurrence.