摘要阿尔茨海默病（AD）是一种进行性加重的神经退行性疾病，也是导致老年人痴呆的主要原因。近年来，无创脑刺激（NIBS）如经颅磁刺激、经颅电刺激、聚焦超声和经颅光生物调节被广泛用于AD患者的治疗。目前NIBS虽然能够改善AD患者的临床症状，但是其疗效尚存在一定争议。本文现围绕近年来NIBS治疗AD的最新研究进展进行综述，以期为临床工作者提供参考。

abstractsAlzheimer's disease (AD) is a kind of progressive neurodegenerative disease, which has become the leading cause of dementia in the elderly. In recent years, non-invasive brain stimulation (NIBS), including transcranial magnetic stimulation, transcranial electrical stimulation, focused ultrasound stimulation and transcranial photobiomodulation, has been widely used in AD treatment. Although NIBS can improve the clinical symptoms of AD patients, its efficacy is still controversial. This article reviews the latest research progress in role of NIBS in AD so as to provide reference for clinical workers.