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胃癌淋巴结转移的临床病理研究

Clinicalpathology of lymphnode metastasis in patients with gastric cancer

摘要用溶脂法检查胃癌根治术后标本的全部淋巴结,28例共检出1965个,平均每例70.18个。结果发现,在292个有癌转移的淋巴结中,61.64%是肉眼难分辨的直径<5mm的,这些小淋巴结以癌占其大部分或全部为主(71.67%),而直径>10mm的仅占12.33%。N 3中绝大多数是直径<5mm淋巴结,其中有癌转移的占61.54%,同时发现有跳跃转移的病例。本研究结果否定了传统的用术中手感、目视等判断淋巴结受累的方法。

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abstractsIn this study, the results of operative resected preparates of 28 cases with gastric cancer by using the lymphnode clearing technique for identifical node was resported. A total of 1965 regional nodes (average 70.18 node/case) were obtained from the R 3 or R 2 resected specimens. Histologically, a total of 292 nodes were found to be involved. It is known that, it was difficult to identifed the node by naked eyes when the diameter 5mm in formalin fixed specimens without dissolving fatty substance in it. Histologically, 71.67% of small (≤5mm diameter) and 12.3% of large size nodes (≥10mm diameter) were metastased, it is noted that in small size nodes the whole node was involved besides in the marginal sinus in the large size node. In N 3, the majority of involved node was small size (≤5mm diameter) and the LNM incidence was higher in small size node (61.54%). In this series, only one case can be observed the phenomenon of "skip metastasis" (ie N 1 N 3 positive node, while N 2 negative node). It is conclude that, traditionally identification of LNM during operation by inspection or palpation is uncertain and showed by negative, until now the traditional method to identify LNM is only by multiple histological section on resected specimens.

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DOI 10.3760/cma.j.issn.1001-9030.1995.02.115
发布时间 2020-11-30(万方平台首次上网日期,不代表论文的发表时间)
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