摘要目的 分析性别因素对下肢动脉硬化性疾病发生及预后的影响.方法 2000年1月至2007年2月共收治842例下肢动脉硬化性闭塞症病例,根据患者的系统情况及患肢的缺血程度,分别采用药物治疗、血管旁路手术和腔内介入等治疗.分析性别对下肢动脉硬化性闭塞症发生及预后的影响.结果 本组患者的男女比例为3.65:1.00,各年龄段男女比例随年龄的增加逐渐减小.男性平均年龄(71.7±9.0)岁,女性平均年龄(75.7±6.8)岁.男性患者髂动脉病变明显多于女性,而女性患者腹股沟以远动脉病变要多于男性.女性患者合并糖尿病的比例为46.4%,明显高于男性的24.7%(P＜0.05).住院患者中女性截肢率较男性高(分别为16.0%和9.1%).结论 下肢动脉硬化性闭塞症男性多于女性,但女性患者预后较男性患者差.

abstractsObjective To evaluate the influence of gender on the development and prognosis of atherosclerosis obliterans(ASO).Methods Eight hundred and forty-two patients with ASO were treated from January 2000 to February 2007.The clinical data were retrospectively collected.And the influence of gender on the development and prognosis of ASO was investigated.Results Among the 842 patients,661 were male and 181 were female.The ratio of male to female was 3.65:1.00,and the ratio decreased with increasing age.The mean age of male and female patients were(71.7±9.0)years and(75.7±6.8)years,respectively.Significantly more iliac lesions occurred in male patients than in female,while female patients experienced more infrainguinal lesions.The coexistence rate of diabetes and amputation rate were significantly higher in female patients than in male(46.4%/24.7% and 16.0%/9.1%,respectively).Conclusion The female patients with ASO appear to have poorer prognosis than the male,despite their lower incidence of ASO.