摘要目的 探讨结直肠癌肺转移的治疗效果和影响预后的因素.方法 回顾性分析1990-2010年收治的结直肠癌肺转移的病例79例,其中行肺转移瘤切除22例,非手术治疗57例.对比肺转移手术治疗与非手术治疗的随访结果,并进行相关因素分析.结果 手术组肺转移瘤切除术后中位生存期为34.5个月,患者l、3、5年生存率分别为90.9％、45.4％和4.5％；非手术组中位生存期16.0个月,肺转移后患者l、3、5年生存率分别为59.6％,14.0％和0.手术与否(RR=4.805,95％CI:1.864 ～ 12.384,P=0.001),肺转移瘤数量(RR =2.177,95％CI:1.431 ～3.314,P=0.010)是影响结直肠癌肺转移预后的独立因素.结论 对于结直肠癌肺转移的患者,手术切除是积极有效的治疗手段.

abstractsObjective To investigate effect of the treatments and prognostic factors of patients with pulmonary metastasis from colorectal cancer.Methods Clinical data of 79 patients who suffered from lung metastatic diseases from colorectal cancer in 1990-2010 were retrospectively analyzed. The number of patients who had received lung operation was 22,and non-operated group contained 57 patients.Compared the prognosis of operated group and non-operated group and analyzed the prognostic factors.Results The median survival time after the pulmonary resections was 34.5 months; the overall survival of 1-,3- and 5-year survival rates were 90.9％,45.4％ and 4.5％,and the overall of 1-,3-,and 5-year survival rate in non-operated group were 59.6％,14.0％ and 0.The surgery (RR =4.805,95％ CI:1.864-12.384,P =0.001 ) and the number of metastasis ( RR =2.177,95％ CI:1.431-3.314,P =0.010) were the factors that could influence the patients prognosis. Conclusion The surgery for pulmonary metastases from colorectal cancer is effective.