摘要肝移植是全球外科领域中的"皇冠"，也是国家医疗水平的重要体现。近半个世纪以来，我国肝移植事业取得了令人瞩目的进步，移植例数位居全球第二，移植存活率达到国际先进水平。但也必须看到我国从肝移植大国迈向强国的过程中，仍然存在诸多瓶颈问题亟须解决，尤其是在精准医学与大数据时代，肝移植基础研究水平相对滞后，无法满足快速发展的临床实践需求。在移植技术日趋成熟而分子生物学技术日新月异的新时代，如何加强肝移植学科领域的基础研究正是科技兴国的重要突破口。只有以多学科融合研究为孵化器，汇集优势资源拓展高水平合作，才能打造一支兼备全局战略目光和创新性思维的高素质攻关团队，才能推进基础研究持续创新发展并产生一批具有国际影响力的科研成果，才能进一步提升我国源头创新能力形成肝移植科技创新高地。

abstractsLiver transplantation(LT) is the "crown" of surgery and is also an important manifestation of national medical standards. In the past half century, China has made remarkable progress in LT. Currently, China is the second largest country of LT world widely and presents an international advanced level in the efficacy of LT. However, it is notable that there are still many bottlenecks to be solved in China. In the era of precision medicine and big data, the basic research of LT is largely lagging behind and unable to meet the rapid development of clinical needs. Strengthen the basic research of LT is a breakthrough strategy in rejuvenating the country through science and technology in the new era. A high-quality professional research team should be built through multi-disciplinary cooperation and superior resources gathering. Researcher′s innovative thinking and strategic vision should be cultivated via the learning of new technologies (e.g., single-cell exploration and multi-omics analysis) and new courses (e.g., transplant oncology and transplant immunology). Government investment also needs to be increased to speed up the nurturing of high-level talents and get great achievements. Basic research is the driving force for China to become a leading country in LT.