摘要胰腺神经内分泌肿瘤的发病率逐年增加，外科治疗过程中仍有许多有争议的问题有待解决。如小的无功能神经内分泌治疗是否均需手术切除；对转移性胰腺神经内分泌肿瘤，原发灶和转移灶是否均需要切除；局限性肿瘤切除术后是否需要辅助治疗；对小的胰腺神经内分泌肿瘤应选择规则切除还是局部切除，对这些问题的回答，一些来源于真实世界的研究已经提供了重要的数据，未来更多高质量的研究有望对这些问题做出满意的回答。

abstractsThe incidence of pancreatic neuroendocrine tumor is increasing gradually in recent years.There are still lots of debated issues in surgical management of this kind of tumor.Whether all small non-functional pancreatic neuroendocrine tumor need to be resected, whether primary and metastatic lesion need to be resected in metastatic disease, whether adjuvant therapy is necessary for resected tumor, whether enucleation is optimal for small pancreatic neuroendocrine tumor.Some data from real world study has provide primary answer to these questions.More high-quality study in the future will provide satisfactory answer.