摘要胰腺癌患者的预后极差。一方面迫切需要寻求便捷高效的早筛早诊新技术将胰腺癌的诊疗窗口前移，另一方面又需深入开展临床基础转化研究以期在胰腺癌治疗领域有所突破。为了改善胰腺癌患者的预后，有必要推进以疾病为中心的诊疗模式，通过多学科团队的有机组合，达成高质量“防、筛、诊、治、康、访”的全周期闭环流程管理，从本质上寻求改善患者结局的康复路径，真正为患者结局负责。本文总结了国内外在胰腺癌全周期管理各阶段的进展并分享该团队近10年的临床经验。

abstractsThe prognosis for pancreatic cancer is extremely poor. To improve the prognosis of pancreatic cancer, it is urgently needed to improve early detection to advance treatment. And basically, it is also necessary to emphasise basic research to find novel therapies. By promoting the disease-centered multidisciplinary team model, researchers should achieve high-quality closed-loop process management of the entire life cycle which consists of prevention, screening, diagnosis, treatment, rehabilitation,and follow-up, with the objective of establishing a standard clinical process to improve the outcome in essence. This article summarized the progress of pancreatic cancer at different stages of the whole cycle management recently and shared the experience of pancreatic cancer treatment from the author′s team in the past ten years.