摘要探究经口内镜下肌切开术治疗食管中段憩室的有效性与安全性。从前瞻性数据库中回顾性纳入2014年4月—2019年9月在四川大学华西医院接受食管憩室经口内镜下肌切开术（diverticular peroral endoscopic myotomy，D-POEM）治疗食管中段憩室的患者，使用适用于食管中段憩室的改良Eckardt评分系统评估憩室症状的严重程度，从临床成功情况、技术成功情况、并发症及复发情况等方面评价其有效性及安全性。共纳入7例食管中段憩室患者，D-POEM治疗临床成功7例，技术成功7例，手术用时为16~70 min；2例发生轻微并发症，无严重并发症，无复发；随访时间为2~16个月，改良Eckardt评分患者中位得分由术前3分降至术后0分。初步认为D-POEM确保了正常食管腔与食管憩室之间间隔肌的完全切开，是一种安全有效的治疗食管中段憩室的技术；改良Eckardt评分系统适用于食管中段憩室治疗前后的症状评价。

abstractsTo investigate the effectiveness and safety of diverticular peroral endoscopic myotomy (D-POEM) for mid-esophageal diverticulum. Data of consecutive patients in the prospective database with mid-esophageal diverticulum who received D-POEM in West China Hospital, Sichuan University between April 2014 to September 2019 were collected. The modified Eckardt scoring system for mid-esophageal diverticulum was used to evaluate the severity of diverticular symptoms. The effectiveness and safety of D-POEM were evaluated in terms of clinical success, technical success, complications and recurrence. A total of 7 patients with mid-esophageal diverticulum were included. Clinical and technical success was achieved in all patients with operation time of 16-70 minutes. No serious complications (2 cases with minor complications) or recurrence occurred. The follow-up time was 2-16 months. The median modified Eckardt score decreased from 3 points before operation to 0 points after operation. It is preliminarily believed that D-POEM ensures a complete septotomy between normal esophageal lumen and esophageal diverticulum. It is a safe and effective technique for mid-esophageal diverticulum. The modified Eckardt scoring system is suitable for symptom evaluation before and after treatment of mid-esophageal diverticulum.