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微创玻璃体切割手术治疗眼弓蛔虫病的疗效观察

Clinical outcome of minimally invasive vitrectomy for ocular toxocariasis patients

摘要目的:观察微创玻璃体切割手术治疗眼弓蛔虫病(OT)的疗效。方法回顾性病例分析。临床检查确诊并接受微创玻璃体切割手术治疗的 OT 患者37例37只眼纳入研究。其中,男性27例27只眼,女性10例10只眼。年龄9个月~22岁,平均年龄(7.90±4.47)岁。能配合检查者均行眼压、裂隙灯显微镜联合+90D 前置镜、激光扫描检眼镜、眼 B 型超声、光相干断层扫描、超声生物显微镜检查。行视力检查35例35只眼,视力无光感~0.6。周边肉芽肿型13只眼;后极部肉芽肿型18只眼;眼内炎型4只眼;不典型型2只眼。牵拉性视网膜脱离(TRD)17只眼;视网膜前膜(ERM)13只眼;TRD 合并 ERM 6只眼;眼内炎1只眼。患眼均行23G 微创玻璃体切割手术。其中,行保留晶状体的玻璃体切割手术25只眼;晶状体切除联合玻璃体切割手术12只眼。采用角膜缘入路5只眼;睫状体平坦部入路32只眼。接受1次手术者32只眼,占86.49%;2次手术者5只眼,占13.51%。手术后随访时间为6~39个月,平均随访时间(13.90±10.25)个月。采用与手术前相同的设备和方法行相关检查,观察患眼视力改善、视网膜复位情况以及有无 ERM 复发和其他并发症的发生。结果行视力检查的35只眼 中,视力提高25只眼,占71.43%;不变9只眼,占25.71%;下降1只眼,占2.86%。TRD 23只眼 中,视网膜复位22只眼,占95.65%;复发性视网膜脱离1只眼,占4.35%。发生并发性白内障3只眼,占保留晶状体眼的12.00%。其中,再次行晶状体切除手术2只眼。ERM 19只眼中,黄斑区视网膜平伏、ERM 未复发18只眼,占94.74%。结论微创玻璃体切割手术治疗 OT 可有效提高患眼视力和视网膜复位率。

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abstractsObjective To observe the clinical outcome of minimally invasive vitrectomy for ocular toxocariasis (OT).Methods The clinical data of 37 eyes in 37 patients with OT who underwent 23-gauge vitrectomy were retrospectively reviewed.There were 27 male patients and 10 female patients.The age was from 9 months to 22 years,with the mean age of (7.90 ± 4.47 ) years.Patients who can cooperate underwent non-contact tonometer examination,slit lamp examination,fundus photography,ultrasound examination,optical coherence tomography and ultrasound biomicroscopic examination.The visual acuity was from no light perception to 0.6.According to the clinical type of OT,18 eyes had posterior granuloma, 13 eyes had peripheral granuloma,4 eyes had endophthalmitis and 2 eyes had atypical presentation. Seventeen eyes had vitrectomy for tractional retinal detachment (TRD),13 eyes for epiretinal membrane (ERM),6 eyes for TRD combined with ERM and 1 eye for endophthalmitis.Twenty-five eyes had lens-sparing vitrectomy,12 eyes had lensectomy with vitrectomy;five eyes had limbus incision and 32 eyes had pars plana incision.Five eyes (13.5 1%)had reoperation.Followed up from 6 months to 39 months, with the mean of (13.90 ± 10.25 )months.Results Vision improved in 25 of 35 eyes (71.43%),was unchanged in 9 eyes (25.71%),and was declined in 1 eye (2.86%).Retina was reattached in 22 of 23 eyes that had TRD before surgery (95.65%);the rest one eye had redetachment (4.35%).Three eyes had cataract after surgery,which accounted for 12% in lens-sparing eyes.Among them,2 eyes had lensectomy therefore.ERM was removed and had no recurrence in 18 of 1 9 eyes (94.74%).Conclusion Minimally invasive vitrectomy for OT patients can improve their vision and achieve retinal reattachment.

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