摘要目的：分析河南省周口市HIV单阳家庭HIV感染者和艾滋病患者的生存质量状况及其相关因素。方法于2015年1—5月，以周口市9个县1个区CDC、乡镇卫生院及村卫生室为依托，按照河南省周口市《HIV感染者和艾滋病患者单阳家庭登记表》，采用方便抽样的方法，纳入经CDC确证HIV单阳家庭中年龄≥18岁者，排除单阳家庭离婚、任意一方死亡或对自己的病情不了解、患有精神疾病和意识障碍、不能够正确理解问卷内容、不愿参与此次调查者，共随访到1251例。采用《WHO生存质量测定简表》中文版和自编问卷对其进行调查，并计算生理领域、心理领域、社会关系领域、环境领域生存质量得分。采用多因素二分类非条件logistic回归模型分析影响调查对象各领域生存质量得分的相关因素。结果调查对象生理领域、心理领域、社会关系领域和环境领域的得分分别为（12.00±2.02）、（12.07±2.07）、（11.87±1.99）和（11.09±1.84）分。<40岁、接受抗病毒治疗和最近2周未患其他疾病者在生理领域的生存质量较好，其OR（95%CI）值分别为0.61（0.35～1.06）、0.52（0.30～0.90）和1.66（1.09～2.52）；非贫困和最近2周未患其他疾病者在心理领域的生存质量较好，其OR （95%CI）值分别为0.15（0.09～0.26）和1.57（1.06～2.33）；<40岁和有子女者在社会关系领域的生存质量较好，其OR（95%CI）值分别为0.58（0.34～0.98）和0.37（0.23～0.57）；有艾滋病相关症状、无子女和最近2周患其他疾病者在环境领域的生存质量得分较低，其OR（95%CI）值分别为0.65（0.48～0.88）、0.66（0.51～0.85）和0.65（0.51～0.84）。结论周口市HIV单阳家庭HIV感染者和艾滋病患者在各领域生存质量较好；年龄、是否有艾滋病相关症状、是否接受抗病毒治疗、有无子女、是否为贫困低保户以及最近2周是否患其他疾病是其生存质量的相关因素。

abstractsObjective To investigate the quality of life and its related factors among HIV/AIDS patients from HIV serodiscordant couples in Zhoukou city of Henan province.Methods During January to May in 2015, by the convenience sample, World Health Organization Quality of Life Questionnaire for Brief Version (WHOQOL?BREF) (Chinese version) and a self?edited questionnaire were used to investigate 1 251 HIV/AIDS patients who were confirmed with HIV positive by local CDC, registered in“HIV serodiscordant family”and agreed to participate in a face?to?face interview with above 18 year?old based on the local CDC , township hospitals and village clinics of 9 counties and 1 district of Zhoukou city, excluding the HIV/AIDS patients who were in divorce, death by one side, unknowing about his HIV status, with mental illness and disturbance of consciousness, incorrectly understanding the content of the questionnaire, and&nbsp;reluctant to participate in this study. The scores of quality of life of physical, psychological, social relations, and environmental domain were calculated. The related factors of the scores of different domains were analyzed by Multiple Two Classification Unconditioned Logistic Regression. Results The scores of investigation objects in the physical, psychological, social relations, and environmental domain were 12.00± 2.02, 12.07 ± 2.07, 11.87 ± 1.99, and 11.09 ± 1.84, respectively. The multiple Unconditioned Logistic Regression analysis indicated that age <40 years, on ART and no other sickness in last two weeks were beneficial factors associated with physical domain with OR (95%CI): 0.61 (0.35-1.06), 0.52 (0.30-0.90), and 1.66 (1.09-2.52), respectively. The possibility of no poverty and no other sickness in last two weeks increased to 0.15(0.09-0.26) and 1.57(1.06-2.33) times of those who was in poverty and with other sickness in last two weeks in physical domain. The possibility of participants who were below 40 years old and with children increased to 0.58 (0.34-0.98) and 0.37 (0.23-0.57) times of who were above 40 years old and without children in psychological domain. The factors of with AIDS related symptoms, no children and with other sickness in last two week were found to be significantly associated with environmental domain with OR (95%CI):0.65 (0.48-0.88), 0.66 (0.51-0.85), and 0.65 (0.51-0.84), respectively . Conclusion The scores of every domain of quality of life in HIV serodiscordant couples of Zhoukou city were good. Age, whether having AIDS related symptoms, whether to accept ART , children, status of poverty, and whether suffering from other diseases in last two weeks were the main factors associated with the quality of life .